Aseem Z. Ansari

This study shows that BRD4 recruitment can desilence transcription within repressive chromatin without removing H3K9me3 or HP1, challenging conventional models of chromatin regulation.

This study compares two models of transcription factor function in yeast, showing that Gcn4 can act through both soluble complexes and condensates, with DNA binding suppressing phase separation.

The paper identifies dynamic DNA secondary structures in vivo that contribute to genome instability by analyzing ssDNA converted to DSBs using S1-END-seq.