H. Siebe Spijker

This study introduces proxiloids, a scalable human-induced pluripotent stem cell differentiation method that models kidney proximal tubule toxicity more accurately than existing methods.

The paper identifies cell type-specific lncRNAs in human kidneys and finds TARID, a podocyte-specific lncRNA, is upregulated in diabetic kidney disease and critical for actin cytoskeleton reorganization.