An in situ generated CAR-M with IFNg and negative dominance Sirpa isoform augments hepatocellular carcinoma immunotherapy
Xiang Li, Jing Hu, Tian Zhang…·Panpan Zhang
This paper develops a novel CAR-M targeting GPC3 with IFN-gamma and SIRPECD to enhance anti-tumor activity in hepatocellular carcinoma.