Author
Columbia UniversityORCID 0000-0001-6168-8644Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
James W. Swann, Jun Hou Fung, Ziwei Chen…·Emmanuelle A. Passegue
The paper identifies shared and distinct molecular mechanisms of emergency myelopoiesis using scRNA-seq and develops tools to annotate and model hematopoietic differentiation.
Oakley C. Olson, Ruiyuan Zhang, Melissa A. Proven…·Emmanuelle A. Passegue
This study identifies glutaminolysis as a therapeutic target to suppress emergency myelopoiesis by targeting glutaminase in hematopoietic stem and progenitor cells.
James W. Swann, Ruiyuan Zhang, Evgenia V. Verovskaya…·Emmanuelle A. Passegue
The paper identifies two bone marrow compartments and shows inflammation affects them differently, with type I interferon causing changes in mesenchymal stromal cells.
Amélie Collins, James W. Swann, Melissa A. Proven…·Emmanuelle A. Passegue
The paper shows maternal IL-10 restricts fetal HSPCs from activating emergency myelopoiesis, leading to reduced myeloid cell production and neonatal neutropenia.