Paul Daniel Arnold

The paper describes the development of a harmonized multisite MRI protocol for pediatric brain imaging and validates its cross-site consistency.

This study identifies unique functional connectivity patterns in autism associated with five sensory processing phenotypes using machine learning.

The paper examines the association between polygenic risk scores, structural brain measurements, and obsessive-compulsive symptoms in adolescents with various psychiatric diagnoses.

This study uses deep learning to predict internalizing problems from brain structure in youth, finding good performance in neurodevelopmental conditions but sub-optimal in the general population.

The paper examines multisensory integration network (MSN) functional connectivity in neurodevelopmental disorders and finds that sensory characteristics, not diagnoses, drive the observed neural patterns.

The paper examines age-related changes in brain structure and function across two neurodiverse datasets, finding differences linked to demographic and clinical factors.

IMAS, a statistical method, uses image-derived phenotypes from the UK Biobank to discover genetic associations with four brain disorders, revealing a common cerebellar mechanism.

This paper conducts a GWAS of subclinical obsessive-compulsive symptoms (OCS) in 33,943 individuals, finding polygenic risk and genetic overlap with OCD.

The paper investigates the association between gene copy number variation and mental health traits in children, finding links to ADHD, OCD, and cognitive biomarkers.

The paper examines associations between externalizing/internalizing behaviors and cortico-amygdalar connectivity in children with NDDs and TDC, finding no significant linear relationships.

This study uses MEG to examine neural activity during a Go/No-Go task in medication-naive OCD youth and typically developing controls, finding altered motor and orbitofrontal cortex responses.

This study identifies white matter microstructural alterations in adult OCD patients and links them to clinical features, while finding no such abnormalities in pediatric patients.

This study characterizes the effects of varying humanized androgen receptor Q tract lengths on brain anatomy and behavior in mice, finding non-linear neuroanatomical changes and no behavioral effects.

The paper integrates brain imaging and behavioral data to identify transdiagnostic subgroups in children with ASD, ADHD, or OCD, finding stable groups based on cortical thickness and inattention symptoms.

The paper identifies shared genetic risk factors between OCD, population-based OCS, and insulin signaling traits, suggesting a common etiological mechanism.

This study compares structural brain differences across ADHD, ASD, and OCD using MRI data from multiple cohorts, finding disorder-specific alterations in brain volume and cortical thickness.

The paper validates the SWAN Scale as a tool for ADHD trait-based genetic research, showing it predicts ADHD diagnoses and is linked to ADHD polygenic risk.

This study investigates the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder using a cross-disorder GWAS, finding a significant genetic correlation and associations with psychiatric and metabolic traits.

The paper investigates the factor structure and heritability of obsessive-compulsive traits in children and adolescents using the TOCS, identifying six dimensions and estimating heritability ranges.