Nora I. Strom

Dog-human gene network colocalization links synaptic signalling and ubiquitination to compulsive disorders

This paper uses GWAS in dogs and humans to identify a gene network linked to compulsive disorders, revealing biological pathways not detectable in human studies alone.

Genome-Wide Association Analysis of Tic Disorders Reveals 6 Independent Risk Loci and Highlights Tic-Associated Cell Types and Brain Circuitry

This study identifies six genome-wide significant risk loci for tic disorders and links genetic risk to specific brain cell types and circuits.

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling

This paper identifies 58 genome-wide significant loci for major anxiety disorders using a large meta-analysis and highlights GABAergic signaling as a potential mechanism.

Genome-wide analyses of quantitative generalised anxiety symptom severity

This study conducts a genome-wide association analysis of generalised anxiety symptom severity, identifying 80 significant variants and showing genetic correlations with other mental and physical health traits.

The Landscape of Shared and Divergent Genetic Influences across 14 Psychiatric Disorders

The paper identifies five genomic factors explaining most genetic variance across 14 psychiatric disorders and finds shared and disorder-specific genetic signals with distinct biological functions.

Genome-wide association study identifies new loci associated with OCD

This study conducts a large-scale GWAS of OCD, identifying 15 new genome-wide significant loci and linking OCD to multiple cortical regions and cell types.

Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population

This paper conducts a GWAS of subclinical obsessive-compulsive symptoms (OCS) in 33,943 individuals, finding polygenic risk and genetic overlap with OCD.

Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

This study identifies four genetic factors underlying 11 psychiatric disorders and finds limited evidence for a single dimension of genetic risk across them.