MicrobiologybioRxivPreprint
Synergistic activity of the ferroptosis inducer RSL3 and Pyrimethamine to inhibit the proliferation of Plasmodium falciparum
Vella Nikolova, Karen Linnemannstöns, Anastasiia Zahoruiko…·Matthias Dobbelstein
This study shows that RSL3 and Pyrimethamine synergistically inhibit Plasmodium falciparum growth, with a mechanism distinct from canonical ferroptosis.
DOI 10.1101/2025.03.14.643256