Author

Ganesh Muthu

Manipal Academy of Higher EducationORCID 0000-0001-6239-6061Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:phylogenetics / evolution· 2 Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1

Frequent Co-Authors

Aswin Sai Narain SeshasayeeiD· 2 shared Sunil LaxmaniD· 2 shared Akshara DubeyiD· 1 shared Edrea MendoncaiD· 1 shared Felix Christian· 1 shared Gaurav SinghiD· 1 shared Kshitija Shetty· 1 shared Sreesa SreedharaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 17 mutual co-author links

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2 shared papersGenomics

Aswin Sai Narain SeshasayeeORCID

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3 papers

Recent·Most cited

GenomicsGenome Biology and EvolutionPeer-reviewedMay 23, 2026

Evolutionary analysis of Trehalose breakdown pathways

Ganesh Muthu, Sunil Laxman, Aswin Sai Narain Seshasayee

This study analyzes the evolutionary distribution of trehalose breakdown pathways across 4000 genomes, revealing ancestral origins and lineage-specific losses.

DOI 10.1093/gbe/evag125

bacteria (other)human

𝕏 PostBluesky

Systems BiologybioRxivPreprintApr 24, 2026

A conserved Pho4-Pho84 axis ubiquitously maintains intracellular phosphate homeostasis in yeast

Sreesa Sreedharan, Kshitija Shetty, Ganesh Muthu…·Sunil Laxman

The paper identifies Pho4-Pho84 as a conserved mechanism for maintaining intracellular phosphate homeostasis in yeast under phosphate-replete conditions.

DOI 10.64898/2026.04.22.720069

yeaststatistical model

𝕏 PostBluesky

GenomicsJournal of Molecular BiologyPeer-reviewedJan 23, 2025

Evolution of transcription factor-containing superfamilies in Eukaryotes

Akshara Dubey, Ganesh Muthu, Aswin Sai Narain Seshasayee

The paper examines the evolutionary dynamics of transcription factor and non-transcription factor DNA-binding superfamilies across eukaryotic clades, revealing differences in their scaling and evolutionary rates.

2 citations

fungi (other)human

𝕏 PostBluesky