Kay Prüfer

This paper confirms the genealogical relationship between Otto I and Heinrich II through ancient DNA analysis and whole-genome sequencing.

This paper presents a second high-quality Denisovan genome from a 200,000-year-old molar, revealing genetic contributions from multiple Denisovan groups and refining the Denisovan genetic lineage.

This study analyzes ancient DNA from the South Caucasus over 5000 years, showing genetic continuity despite high mobility and admixture from Anatolia, the steppe, and southern populations.

The paper reports a high-coverage Neandertal genome from Chagyrskaya Cave, revealing genetic features unique to Neandertals and population structure insights.

The paper uses a Bayesian method to infer ancient demographic events and finds evidence of migration from Eurasian ancestors into Africa 40-70 thousand years ago.

Genome-wide and isotopic data from prehistoric Sicilians reveal a pre-farming connection to (south-) eastern Europe, and tentative initial evidence that hunter-gatherers adopted some Neolithic aspects prior to near-total replacement by early farmers.

The paper develops a method to reduce spurious alignments in ancient DNA sequences, increasing usable data from degraded samples and placing a third specimen on the Neandertal lineage.

The paper detects systematic errors in large genomic datasets by analyzing batch effects, finding coding regions have more errors than non-coding regions.

snpAD improves genotype calling from ancient DNA by accounting for sequence errors, showing lower heterozygosity in Neandertals compared to modern humans.

This study detects ancient positive selection in humans by identifying genomic regions where Neandertals and Denisovans fall outside present-day human variation, finding evidence for regulatory changes associated with human-specific traits.

The paper analyzes ancient genomes to show present-day Europeans derive from three populations: WHG, ANE, and EEF, with EEF having Basal Eurasian ancestry.