NeuroscienceScience AdvancesPeer-reviewed
The temporal balance between self-renewal and differentiation of human neural stem cells requires the Amyloid Precursor Protein
Khadijeh Shabani, Julien Pigeon, Marwan Benaissa Touil Zariouh…·Bassem A. Hassan
This study shows that Amyloid Precursor Protein (APP) is required for human neural stem cells to maintain a progenitor state during prolonged neurogenesis, unlike mouse NSCs where APP is dispensable.
22 citations