Julien Pigeon

Post-translational Tuning of Human Cortical Progenitor Neuronal Output

The paper identifies phosphorylation of NEUROGENIN2 as a regulator of human radial glial cell neuronal output, leading to increased production of upper-layer neurons.

The temporal balance between self-renewal and differentiation of human neural stem cells requires the Amyloid Precursor Protein

This study shows that Amyloid Precursor Protein (APP) is required for human neural stem cells to maintain a progenitor state during prolonged neurogenesis, unlike mouse NSCs where APP is dispensable.

The ribose methylation enzyme FTSJ1 has a conserved role in neuron morphology and learning performance

The paper identifies a novel FTSJ1 pathogenic variant and shows its role in neuron morphology and learning performance through RiboMethSeq and transcriptome analysis in human and Drosophila models.