Author

Mercedes Robledo

Spanish National Cancer Research CentreORCID 0000-0001-6256-5902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Nicole BechmanniD· 3 shared Mirko PeitzschiD· 2 shared Alberto CascóniD· 1 shared Alexander R. OpotowskyiD· 1 shared Alexandre BuffetiD· 1 shared Alicia ArenasiD· 1 shared Amelia OleagaiD· 1 shared Ana Belén Moreno-CárdenasiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

Nicole BechmannORCID

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3 papers

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedApr 8, 2025

Convergent genetic adaptation in human tumors developed under systemic hypoxia and in populations living at high altitudes

Carlota Arenillas, Lucía Celada, José Ruiz-Cantador…·Rodrigo Almeida Toledo

This study links EPAS1HIF2 genetic adaptations in high-altitude populations to similar mutations in hypoxia-driven tumors, showing shared mechanisms in hypoxia response and tumorigenesis.

14 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 18, 2025

A genetic signature predicts aggressive paraganglioma sensitivity to dual PI3K-CDK4/6 inhibition therapy

Bhargavi Karna, Federica Gentile, Sebastian Gulde…·Natalia Simona Pellegata

1 citation

humanrat

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Cancer BiologybioRxivPreprintJan 24, 2025

Identification of a novel papillary renal cell carcinoma molecular subtype characterized by HIF-pathway over-activation

Javier de Nicolás‐Hernández, Alicia Arenas, Carlos Valdivia…·Cristina Rodríguez‐Antona

This paper identifies a novel molecular subtype of papillary renal cell carcinoma (pRCC) characterized by HIF-pathway overactivation, associated with poor prognosis and distinct biological features.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky