Author

Andreas Weihofen

Biogen (United States)ORCID 0000-0001-6265-9087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Ahmad Allouche· 1 shared Alessandro MichelucciiD· 1 shared Alix BoomsiD· 1 shared Allyson Cole-Strauss· 1 shared Annette MasuchiD· 1 shared Apoorva Mohan· 1 shared Brian F. Daley· 1 shared C. Frank BennettiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Ahmad Allouche

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 5, 2020

Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson disease

Pierre Garcia, Wiebke M. Wemheuer, Oihane Uriarte Huarte…·Manuel Buttini

The paper investigates the role of alpha-synuclein spreading and inclusions in Parkinson disease using a mouse model, finding that neurodegeneration and microgliosis occur independently of inclusions.

1 citation

mousestatistical model

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 4, 2019

Alpha-synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson’s disease

Tracy A. Cole, Hien Tran Zhao, Timothy J. Collier…·Katrina L. Paumier

This paper demonstrates that antisense oligonucleotides targeting SNCA reduce alpha-synuclein production, prevent pathology, and show translational potential in non-human primates.

10 citations

mousenon-human primate

𝕏 PostBluesky