Author

Thomas Ipoutcha

Imperial College LondonORCID 0000-0001-6266-9381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 3 Research Focus:gene regulatory network inference· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Alain BlanchardiD· 2 shared Carole LartigueiD· 2 shared Fabien RideauiD· 2 shared Géraldine GourguesiD· 2 shared Pascal Sirand‐PugnetiD· 2 shared C. WilsoniD· 1 shared Eduardo P. C. RochaiD· 1 shared Egon Anderson OzeriD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

Alain BlanchardORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 30, 2026

An improved CRISPR-base editor tool to target virulence factors in the ruminant pathogen Mycoplasma bovis

Patrick J Hogan, Marc Duclusaud, Thomas Ipoutcha…·Fabien Rideau

The paper improves a CRISPR-base editor tool for targeting virulence factors in Mycoplasma bovis by enabling multi-loci targeting and expanding targetable loci.

DOI 10.64898/2026.05.29.712936

bacteria (other)experimental assay

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MicrobiologybioRxivPreprintFeb 5, 2026

Mobile genetic elements drive a fusion-deletion life cycle that shapes plasmid evolution and antimicrobial resistance

Thomas Ipoutcha, Yiqing Wang, Eduardo P. C. Rocha, José R. Penadés

The paper shows mobile genetic elements drive a fusion-deletion cycle in plasmids, shaping their evolution and antimicrobial resistance in Staphylococcus aureus.

4 citations

bacteria (other)whole-genome sequencing

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Synthetic BiologyMicrobiology SpectrumPeer-reviewedJan 31, 2024

A synthetic biology approach to assemble and reboot clinically-relevant Pseudomonas aeruginosa tailed phages

Thomas Ipoutcha, Ratanachat Racharaks, Stefanie Huttelmaier…·Erica Marie Hartmann

This paper develops a synthetic biology method to construct and reboot clinically-relevant Pseudomonas aeruginosa phages, demonstrating successful cloning, assembly, and rebooting in different bacterial strains.

20 citationstop 4%

bacteria (other)experimental assay

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Synthetic BiologyACS Synthetic BiologyPeer-reviewedOct 16, 2023

Combining fusion of cells with CRISPR-Cas9 editing for the cloning of large DNA fragments or complete bacterial genomes in yeast.

Gabrielle Guesdon, Géraldine Gourgues, Fabien Rideau…·Carole Lartigue

The paper introduces a new method combining Fusion cloning and CRISPR-Cas9 to clone and edit large bacterial genomes in yeast, demonstrating its effectiveness with Mycoplasma species.

9 citations

yeastexperimental assay

𝕏 PostBluesky