Author

Kehan Wu

Loyola University ChicagoORCID 0000-0001-6273-2029Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:large language model· 1 Research Focus:perturbation response prediction· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

Chi-Kin Chan· 1 shared Enhong CheniD· 1 shared Haiguang LiuiD· 1 shared Han Jie GuoiD· 1 shared Hiral P. PateliD· 1 shared Huini WuiD· 1 shared Jinjiang GuoiD· 1 shared Jinzhi Wu· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Chi-Kin Chan

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologyMolecular Biology of the CellPeer-reviewedJun 11, 2025

Non-muscle myosin 2 can incorporate into established filaments in cells without an assembly competence domain

Kehan Wu, Hiral P. Patel, Huini Wu…·Jordan R. Beach

This study shows that non-muscle myosin 2A lacking the ACD can co-assemble with existing filaments, indicating the ACD is not required for association with established filaments.

DOI 10.1091/mbc.e24-07-0287

humanexperimental assay

𝕏 PostBluesky

BiochemistryNature CommunicationsPeer-reviewedOct 29, 2024

Target-aware Molecule Generation for Drug Design Using a Chemical Language Model

Kehan Wu, Yingce Xia, Pan Deng…·Tie‐Yan Liu

This paper introduces TamGen, a chemical language model for target-aware molecule generation, and shows it produces high-quality compounds with inhibitory activity against Tuberculosis ClpP protease.

107 citationstop 1%

deep learninglarge language model

𝕏 PostBluesky