Timothy W. Chapman

The paper identifies transient procaspase-3 upregulation in differentiating oligodendrocytes and shows its role in promoting differentiation and survival decisions.

This study shows that oligodendrocyte maturation changes cell death mechanisms, with precursor cells dying quickly and mature cells dying slowly after genotoxic damage.

This study investigates age-related differences in remyelination by NG2-glia using a novel demyelination model and finds that remyelination efficiency declines with age due to failed oligodendrogenesis.

The paper describes a synthetic bio-molecular operational amplifier using 5 proteins to enable robust, precise, and programmable homeostasis and regulation in living cells.