Author

Colin P. Florian

Washington University in St. LouisORCID 0000-0001-6309-5199Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Courtney F. JungersiD· 2 shared Joseph D. DoughertyiD· 2 shared Sergej DjuranovićiD· 2 shared Aishwarya NambiariD· 1 shared Benjamin D. BorosiD· 1 shared Dylan A. Galloway· 1 shared Kathleen M. SchochiD· 1 shared Kelli McFarland WhiteiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Courtney F. JungersORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 17, 2026

Protein expression is amplified by stabilizing mRNA using gene-specific antisense oligonucleotides

Benjamin D. Boros, Aishwarya Nambiar, Miwei Hu…·Timothy M. Miller

The paper demonstrates that antisense oligonucleotides (ASOs) can upregulate gene expression by stabilizing mRNA through targeting destabilizing elements like PREs, with therapeutic implications for haploinsufficiency disorders.

DOI 10.64898/2026.09.14.749961

humanmouse

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Genetic & Genomic MedicinemedRxivPreprintNov 2, 2023

A Massively Parallel Screen of 5'UTR Mutations Identifies Variants Impacting Translation and Protein Production in Neurodevelopmental Disorder Genes

Stephen P. Plassmeyer, Colin P. Florian, Michael J. Kasper…·Joseph D. Dougherty

The paper screens 5'UTR mutations in neurodevelopmental disorder genes to identify functional variants impacting translation and protein production, finding some mutations affect known syndromic autism genes in neurons.

11 citations

humanwhole-genome sequencing

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