Cancer BiologybioRxivPreprint
Dexamethasone-Induced p57-Mediated Quiescence Drives Chemotherapy Resistance in Sonic Hedgehog Medulloblastoma
Aryaman Sharma, Lauren Ellis, Kaytlin Andrews…·James Purzner
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Stanford MedicineORCID 0000-0001-6313-256XUnclaimed ORCID profile · follow to get notified of new preprints
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Aryaman Sharma, Lauren Ellis, Kaytlin Andrews…·James Purzner
James Purzner, Alexander S. Brown, Teresa Purzner…·Matthew P. Scott
This study shows Ezh2 suppresses differentiation gene activation in cerebellar granule neurons and medulloblastoma cells, and its inhibition combined with cell cycle exit promotes differentiation.