Author

Kathryn J. Farrand

Malaghan Institute of Medical ResearchORCID 0000-0001-6320-6960Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Ian F. HermansiD· 2 shared Adam Vorn Patterson· 1 shared Alisha R. DabbiD· 1 shared Amir AshoorzadehiD· 1 shared Anton J. CozijnseniD· 1 shared Ariane R. LeeiD· 1 shared Benjamin J. ComptoniD· 1 shared Christopher P. GuiseiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Ian F. HermansORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 12, 2026

Optimization of a liver Trm cell-inducing mRNA vaccine by reduction of type I interferon response

Jordan James Minnell, Mitch Ganley, Ariane R. Lee…·Ian F. Hermans

This study optimizes an mRNA vaccine to enhance liver Trm cell induction by reducing type I interferon responses through improved manufacturing.

DOI 10.64898/2026.05.07.723643

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 24, 2025

Tarloxotinib targets tumor hypoxia to improve therapeutic efficacy of immune checkpoint inhibition in a TLR9 dependent manner

Zhe Fu, Victoria Jackson-Patel, Kathryn J. Farrand…·Adam Vorn Patterson

This paper shows that tarloxotinib, a hypoxia-activated prodrug, reduces tumor hypoxia and enhances immune checkpoint inhibitor efficacy through TLR9-dependent mechanisms in multiple tumor models.

DOI 10.1101/2025.02.24.635378

mousebulk RNA-seq

𝕏 PostBluesky