ImmunologybioRxivPreprint
Rab11FIP2 controls NLRP3 inflammasome activation through Rab11b
Caroline Gravastrand, Maria Yurchenko, Stine Kristensen…·Harald Husebye
This study shows Rab11-FIP2 and Rab11b regulate NLRP3 inflammasome activation in human macrophages by controlling caspase-1 cleavage, pyroptosis, and NLRP3 translocation to the trans-Golgi network.
2 citations