Maria Yurchenko

This study shows that cell-intrinsic complement C3 suppresses IFN-β production in macrophages by limiting IRF3-TBK1 complex formation.

The paper demonstrates methods to restore hematocrit during MPS-cytoblockade, preserving nanoparticle circulation and tumor targeting without compromising safety.

This study identifies P7-Pen as a peptide that enhances monocyte inflammatory responses in sepsis by modulating histone acetylation through ABHD14B.

This study identifies a peptide that inhibits TLR7- and TLR8-induced type I IFN responses by disrupting TIRAP-MyD88 interaction, with species-specific effects observed.

This study shows Rab11-FIP2 and Rab11b regulate NLRP3 inflammasome activation in human macrophages by controlling caspase-1 cleavage, pyroptosis, and NLRP3 translocation to the trans-Golgi network.

This study identifies a SLAMF1-derived peptide, P7N4, that induces apoptosis in multiple myeloma cells by degrading IRF4, enhancing chemotherapy efficacy and showing minimal toxicity to healthy cells.