Author

Hao Guo

Chinese Academy of SciencesORCID 0000-0001-6336-4889Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein sequence· 1 Research Focus:sequence-to-function modeling· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Chen Zheng· 1 shared Chen‐Zhu WangiD· 1 shared Chenmao Zhou· 1 shared Hualiang JiangiD· 1 shared Jie ChangiD· 1 shared Keke ZhangiD· 1 shared Lifan CheniD· 1 shared Ling‐Qiao HuangiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Chen Zheng

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 26, 2022

Drug design and repurposing with a sequence-to-drug paradigm

Lifan Chen, Zisheng Fan, Jie Chang…·Mingyue Zheng

This paper introduces a sequence-to-drug paradigm using TransformerCPI2.0 to discover drug-like molecules from protein sequences and validates its effectiveness for three targets.

1 citation

protein sequencedeep learning

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NeuroscienceInsect Biochemistry and Molecular BiologyPeer-reviewedFeb 16, 2021

Contribution of odorant binding proteins to olfactory detection of (Z)-11-hexadecenal in Helicoverpa armigera

Hao Guo, Pingping Guo, Ya-Lan Sun…·Chen‐Zhu Wang

The paper investigates the role of odorant binding proteins in the olfactory detection of Z11-16:Ald in Helicoverpa armigera, finding that PBPs enhance sensitivity but not selectivity.

32 citations

experimental assay

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