NeuroscienceACS Chemical NeurosciencePeer-reviewed
Sequestration of TDP-43216-414 aggregates by cytoplasmic expression of the proSAAS chaperone
Juan R. Peinado, Kriti Chaplot, Timothy S. Jarvela…·Iris Lindberg
This study shows that cytoplasmic proSAAS forms liquid-like condensates that sequester TDP-43 aggregates, providing cytoprotection against toxicity in yeast.
16 citations