Author

Chisae Nagiri

The University of TokyoORCID 0000-0001-6379-3894Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Akiko OgawaiD· 2 shared Fan‐Yan WeiiD· 2 shared Osamu NurekiiD· 2 shared Wataru ShihoyaiD· 2 shared Aika Iwama· 1 shared Asuka InoueiD· 1 shared Fumiya K. SanoiD· 1 shared Hidenobu TaniharaiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

Akiko OgawaORCID

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2 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedNov 7, 2024

Structural insights into the agonist selectivity and structure-based engineering of the adenosine A3 receptor

Hidetaka S. Oshima, Akiko Ogawa, Fumiya K. Sano…·Osamu Nureki

The paper identifies a novel A3R-selective ligand and reveals structural insights into A3R activation, enabling structure-guided engineering of m6A-insensitive A3R for drug discovery.

15 citations

humanstructural biology

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Molecular BiologyMolecular CellPeer-reviewedJan 19, 2021

N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand

Akiko Ogawa, Chisae Nagiri, Wataru Shihoya…·Fan‐Yan Wei

The paper identifies m6A as an endogenous ligand for the A3 adenosine receptor, showing it has higher affinity than unmodified adenosine and plays a role in type I allergy.

50 citations

statistical model

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