Taylor A. Pursell

This study shows H5N1 clade 2.3.4.4b viruses bind human MHC-II HLA-DR for cell entry, independent of sialic acid, and identifies host genetic and antibody factors that modulate this interaction.

The paper identifies a disrupted CCR5-like immunoglobulin gene in black-footed ferrets linked to increased susceptibility to plague caused by Yersinia pestis.

The paper generates a bat genome and germline immunoglobulin loci to study B cell receptors, finding unique features and differences compared to humans.

The paper identifies two distinct and functional immunoglobulin heavy chain loci in big brown bats, revealing a novel mechanism for humoral immunity potentially linked to viral resistance.