Guizhong Cui

This study identifies Smarcc1's role in optic stalk development and optic nerve head astrocyte differentiation, showing its necessity for morphogenesis and RGC survival.

This study creates a 3D spatial transcriptome atlas of mouse embryos at embryonic day 13.5, integrating with single-cell data to reveal molecular regulation of organ development.

The paper constructs a single-cell spatio-temporal atlas of molecular trajectories during gastrulation in mouse embryos, revealing asymmetric BMP signaling and its role in left-right body plan asymmetry.

The paper maps the spatiotemporal gene expression and cell-cell interactions in a mouse model of acute spinal cord injury, identifying key molecular features and cell types involved in early injury response and recovery.

The paper maps spatial and molecular changes in germ layers during primate gastrulation using spatial transcriptomics and 3D modeling.

This study introduces MISAR-seq to jointly profile spatial gene expression and chromatin accessibility in developing mouse brains, revealing spatiotemporal regulatory principles.