A microRNA program controls the transition of cardiomyocyte hyperplasia to hypertrophy and stimulates mammalian cardiac regeneration
Andrea Raso, Ellen Dirkx, Vasco Sampaio‐Pinto, Hamid el Azzouzi, Ryan John Cubero, Daniel W. Sorensen, Lara Ottaviani, Servé Olieslagers, Manon M. H. Huibers, Roel A. de Weger, Sailay Siddiqi, Silvia Moimas, Consuelo Torrini, Lorena Zentillin, Luca Braga, , León J. De Windt
This study identifies miR-106b~25 as a regulator of cardiomyocyte hyperplasia to hypertrophy transition and shows its ability to induce cardiac regeneration in adult mice.
Nature Communications · Aug 10, 2021Peer-reviewedMolecular Biology