Author

Roel A. de Weger

University Medical Center Utrecht

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Manon M. H. HuibersiD· 2 shared Alain van MiliD· 1 shared Andrea Raso· 1 shared Aryan VinkiD· 1 shared Boudewijn M.T. BurgeringiD· 1 shared C. Snijders BlokiD· 1 shared Caroline ChengiD· 1 shared Consuelo TorriniiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Manon M. H. HuibersORCID

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2 papers

Recent·Most cited

A microRNA program controls the transition of cardiomyocyte hyperplasia to hypertrophy and stimulates mammalian cardiac regeneration

Andrea Raso, Ellen Dirkx, Vasco Sampaio‐Pinto, Hamid el Azzouzi, Ryan John Cubero, Daniel W. Sorensen, Lara Ottaviani, Servé Olieslagers, Manon M. H. Huibers, Roel A. de Weger, Sailay Siddiqi, Silvia Moimas, Consuelo Torrini, Lorena Zentillin, Luca Braga, , León J. De Windt

This study identifies miR-106b~25 as a regulator of cardiomyocyte hyperplasia to hypertrophy transition and shows its ability to induce cardiac regeneration in adult mice.

Nature Communications · Aug 10, 2021Peer-reviewedMolecular Biology

Transcriptional regulation profiling reveals disrupted lipid metabolism in failing hearts with a pathogenic phospholamban mutation

Jiayi Pei, Renée G. C. Maas, Ema Nagyova, Johannes M.I.H. Gho, C. Snijders Blok, Iris van Adrichem, Jorg J. A. Calis, René van Es, Shahrzad Sepehrkhouy, Dries A. M. Feyen, Noortje A. M. van den Dungen, Nico R. Lansu, Nicolaas de Jonge, Hester M. den Ruijter, Manon M. H. Huibers, , Magdaléna Harakaľová

The paper investigates epigenetic and transcriptional changes in PLN R14del cardiomyopathy, identifying disrupted lipid metabolism and altered gene regulation.

bioRxiv · Nov 30, 2020 · PreprintGenomics