Max R. Bernstein

The paper investigates inbreeding depression in Caenorhabditis species, finding it universal but variable, with some species showing low depression and potential as models for outcrossing systems.

The paper shows that polygenic demographic variation in C. elegans is driven by tightly-linked antagonistic-effect loci, with large-effect variants masked by epistasis or linkage disequilibrium.

The paper investigates fine-scale crossover rate variation on the C. elegans X chromosome and finds lower variation compared to other species, with no evidence of hotspots.