Myeloid cell-associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing
Li Wang, John P. Sfakianos, Kristin G. Beaumont, Güray Aktürk, Amir Horowitz, Robert Sebra, Adam M. Farkas, Sacha Gnjatic, Austin Hake, Sudeh Izadmehr, Peter N. Wiklund, William K. Oh, Péter Márton Szabó, Megan Wind‐Rotolo, Keziban Ünsal-Kaçmaz, , Matthew D. Galsky
The paper identifies proinflammatory monocytes/macrophages associated with resistance to PD-1/PD-L1 blockade in urothelial cancer using bulk and single-cell RNA sequencing.
Clinical Cancer Research · Apr 9, 2021Peer-reviewedGenomics