Author

John P. Sfakianos

Icahn School of Medicine at Mount SinaiORCID 0000-0002-3101-0266Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Amir HorowitziD· 3 shared Adam M. FarkasiD· 2 shared Matthew D. GalskyiD· 2 shared Nina BhardwajiD· 2 shared Alexander M. TsankoviD· 1 shared Anna S. TochevaiD· 1 shared Ante PerosiD· 1 shared Aparna AnanthanarayananiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Amir HorowitzORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 31, 2026

Organoid-T cell co-cultures functionally stratify tumor-reactive T cells and their responses to immune checkpoint inhibitors

Elliot Merritt, Julie-Ann Cavallo-Fleming, Genesis Lara Granados…·Anna S. Tocheva

DOI 10.64898/2026.05.27.727968

humanorganoid / primary culture

𝕏 PostBluesky

ImmunologybioRxivPreprintApr 30, 2024

Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling

Adam M. Farkas, Dina Youssef, Michelle A. Tran…·Nina Bhardwaj

This study identifies SLAMF6 signaling suppression in bladder cancer tumor microenvironment as a cause of NK cell dysfunction, showing restoration of function under normoxic conditions.

3 citations

𝕏 PostBluesky

GenomicsClinical Cancer ResearchPeer-reviewedApr 9, 2021

Myeloid cell-associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing

Li Wang, John P. Sfakianos, Kristin G. Beaumont…·Matthew D. Galsky

The paper identifies proinflammatory monocytes/macrophages associated with resistance to PD-1/PD-L1 blockade in urothelial cancer using bulk and single-cell RNA sequencing.

97 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky