MicrobiologybioRxivPreprint
Copy number of the blaNDM-1 gene (New Delhi metallo-β-lactamase-1) and meropenem susceptibility in Enterobacterales: Consideration for treatment with meropenem?
Amrita Bhattacharjee, Soumalya Banerjee, Sanjib Das…·Sulagna Basu
This study investigates why some blaNDM-1-positive Enterobacterales are susceptible to meropenem despite carrying the gene, finding lower gene copy numbers and expression correlate with reduced MIC values, supporting meropenem's efficacy in these cases.
DOI 10.1101/2025.09.03.673909