Sulagna Basu

Genomic characterization of type I-E* CRISPR-Cas systems in Klebsiella pneumoniae: association of spacer diversity and antimicrobial resistance

This study examines CRISPR-Cas systems in Klebsiella pneumoniae, finding no significant association between CRISPR-Cas and multidrug resistance, but noting diverse spacers in non-MDR strains targeting ARG-bearing plasmids.

Copy number of the blaNDM-1 gene (New Delhi metallo-β-lactamase-1) and meropenem susceptibility in Enterobacterales: Consideration for treatment with meropenem?

This study investigates why some blaNDM-1-positive Enterobacterales are susceptible to meropenem despite carrying the gene, finding lower gene copy numbers and expression correlate with reduced MIC values, supporting meropenem's efficacy in these cases.

Co-existence of plasmid-mediated blaNDM-1 and blaNDM-5 in Escherichia coli sequence type 167 and ST101 and their discrimination through restriction digestion

This study identifies and characterizes co-existing blaNDM-1 and blaNDM-5 variants in E. coli isolates using Sanger sequencing and hybrid assembly, and develops a restriction digestion method to distinguish them.