Author

Guido Pacini

Max Planck Institute for Molecular GeneticsORCID 0000-0001-6506-6949Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Edda G. SchulziD· 2 shared Ilona Dunkel· 2 shared Abhishek Sampath KumariD· 1 shared Afrah Ghauri· 1 shared Alexander MeissneriD· 1 shared Annalisa MarsicoiD· 1 shared Bernd Timmermann· 1 shared Gemma NovielloiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetics

Edda G. SchulzORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 2, 2022

GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of a distal enhancer element

Liat Ravid Lustig, Abhishek Sampath Kumar, Till Schwämmle…·Edda G. Schulz

This study identifies GATA transcription factors as essential for initiating Xist upregulation and X-chromosome inactivation in mouse embryos through direct activation of a distal enhancer.

3 citations

mousestatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintJul 20, 2020

Integrated analysis of Xist upregulation and gene silencing at the onset of random X-chromosome inactivation at high temporal and allelic resolution

Guido Pacini, Ilona Dunkel, Norbert Mages…·Edda G. Schulz

The paper uses allele-specific single-cell RNA-sequencing to study Xist upregulation and gene silencing during X-chromosome inactivation in mouse embryonic stem cells, identifying Nanog downregulation as a trigger and genetic variation's role in XCI.

1 citation

mousescRNA-seq

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