Abhishek Sampath Kumar

This study shows human brain organoids can mature over 5 years in culture, transcriptionally aging and retaining memory of time spent in vitro.

This study compares six sequencing-based spatial transcriptomic methods using reference tissues, highlighting molecular diffusion as a key variable affecting resolution and identifying unique attributes of spatial transcriptomic data.

This study identifies GATA transcription factors as essential for initiating Xist upregulation and X-chromosome inactivation in mouse embryos through direct activation of a distal enhancer.

This study investigates the emergence and patterning dynamics of mouse definitive endoderm using in vivo and in vitro models, revealing self-sorting and Sox17 expression patterns.

The paper describes a method to generate trunk-like structures from mouse embryonic stem cells that mimic embryonic development features.