Daniela Wesch

This study shows L1CAMxCD3 bispecific antibodies effectively target PDAC cells in immunosuppressive models, inducing apoptosis and T cell effector molecule release.

This study evaluates BLN-driven cytotoxicity in β and γδ T-cell subsets, finding β T cells show superior cytotoxicity while γδ T cells exhibit stable effector-memory states and reduced susceptibility to activation-induced cell death.

This paper introduces a multifunctional fusion protein that enables efficient ex vivo expansion of NK cells from various sources and enhances their cytotoxic activity against tumor cells.