Author

Guranda Chitadze

Christian-Albrechts-Universität zu KielORCID 0000-0001-9609-4643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Claudia Dorothea BaldusiD· 2 shared Daniela WeschiD· 2 shared Hans‐Heinrich ObergiD· 2 shared Monika BrüggemanniD· 2 shared Sonja BendigiD· 2 shared Thomas ValeriusiD· 2 shared Alexander Jochimsen· 1 shared Alexander ScheffoldiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

Claudia Dorothea BaldusORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Blinatumomab-driven T-cell activation in αβ and γδ T-cell subsets: Insights from in vitro assays

Miriam Kelm, Nourhan Nasr, Sonja Bendig, Dieter Kabelitz, Marta Lustig, Heiko Trautmann, Anna Laqua, Christian Peters, Daniela Wesch, Hans‐Heinrich Oberg, Ottmar Janßen, Thomas Valerius, Claudia Dorothea Baldus, Alexander Scheffold, Monika Brüggemann, Guranda Chitadze

This study evaluates BLN-driven cytotoxicity in β and γδ T-cell subsets, finding β T cells show superior cytotoxicity while γδ T cells exhibit stable effector-memory states and reduced susceptibility to activation-induced cell death.

Frontiers in Immunology · Feb 6, 2026Peer-reviewedImmunology

A Novel Natural Killer Cell Expansion Technology for the Development of Cellular Immunotherapies

Ammelie Svea Boje, Anna Langner, Alexander Jochimsen, Carina Lynn Gehlert, Steffen Krohn, Dorothee Winterberg, Sonja Bendig, Eva Maria Murga Penas, Guranda Chitadze, Monika Brüggemann, Lars R. Fransecky, Katharina Diemer, Dirk Bauerschlag, Natalie Baum, Daniela Wesch, , Matthias Peipp

This paper introduces a multifunctional fusion protein that enables efficient ex vivo expansion of NK cells from various sources and enhances their cytotoxic activity against tumor cells.

bioRxiv · Jan 22, 2026 · PreprintImmunology