Thomas Pap

This study shows that integrin alpha11beta1 promotes joint destruction in arthritic mice, and its deficiency reduces disease severity.

The paper identifies head-to-tail DNA template insertions in CRISPR/Cas9 editing and highlights the failure of PCR to detect them, advocating for comprehensive analysis.

CRUP predicts condition-specific regulatory units by analyzing histone modification ChIP-seq data and linking enhancers to target genes in rheumatoid arthritis.