Anna Ramisch

Microbiopsy of living mouse brain for longitudinal molecular profiling

This paper introduces a minimally invasive microbiopsy technique for longitudinal molecular profiling of the living mouse brain, enabling transcriptomic and epigenomic analyses without sacrificing the animal.

Chondrogenic Enhancer Landscape of Limb and Axial Skeleton Development

The paper maps chondrogenic enhancers in limb and axial skeleton development and shows their role in explaining human height heritability.

Reconceptualising resilience within a translational framework is supported by unique and brain-region specific transcriptional signatures in mice

The paper identifies three phenotypic subgroups of mice following chronic social defeat and finds brain-region specific transcriptional signatures associated with each subgroup.

Leveraging interindividual variability of regulatory activity refines genetic regulation of gene expression in schizophrenia

The paper integrates regulatory activity variability with gene expression and genotype data to identify genetic regulation changes in schizophrenia.

Genetic variation in correlated regulatory region of Immunity

The paper identifies regulatory domains in immune cells using genomic and epigenomic data, revealing cell-type specific gene regulation and genetic control of regulatory elements.

The molecular basis, genetic control and pleiotropic effects of local gene co-expression

The paper identifies local gene co-expression patterns across human tissues and links them to eQTLs associated with multiple traits.

CRUP: A comprehensive framework to predict condition-specific regulatory units

CRUP predicts condition-specific regulatory units by analyzing histone modification ChIP-seq data and linking enhancers to target genes in rheumatoid arthritis.