Author

Noor Chalhoub

NYU Langone HealthORCID 0000-0001-6545-4618Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:benchmarking· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jef D. BoekeiD· 3 shared Ran BroshiD· 3 shared Weimin ZhangiD· 3 shared Matthew T. MauranoiD· 2 shared Aleksandra M. WudzinskaiD· 1 shared Álvaro FajardoiD· 1 shared André Mauricio Ribeiro-dos-SantosiD· 1 shared Antonio Vela GartneriD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersSynthetic Biology

Jef D. BoekeORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintMar 17, 2026

Improved vector toolkit for genome writing in mammalian cells

Kelly Barriball, Brianna Berrios, Camila Coelho…·Ran Brosh

The paper introduces an improved plasmid toolkit to streamline the mSwAP-In method for large-scale genome writing in mammalian cells.

DOI 10.64898/2026.03.15.711894

mouseexperimental assay

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GeneticsbioRxivPreprintJan 5, 2026

Genome writing and Targeted Delivery of the NKX6-3/ANK1 gene cluster and its Type 2 Diabetes GWAS Variants to Human iPSCs

Noor Chalhoub, Arushi Varshney, Weimin Zhang…·Jef D. Boeke

This paper introduces a method to deliver synthetic haplotypes containing T2D GWAS variants to hiPSCs to study their functional impact on differentiation.

DOI 10.64898/2026.01.04.697539

humanCRISPR screen

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GenomicsNaturePeer-reviewedNov 1, 2023

Mouse genomic rewriting and tailoring: synthetic Trp53 and humanized ACE2

Weimin Zhang, Ilona Golynker, Ran Brosh…·Jef D. Boeke

This paper introduces mSwAP-In, a method for efficient genome rewriting in mouse embryonic stem cells, demonstrating its use for Trp53 and ACE2 locus modifications to create more accurate disease models.

50 citationstop 4%

mouseexperimental assay

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GenomicsbioRxivPreprintNov 29, 2021

Transposon Extermination Reveals Their Adaptive Fitness Contribution

Susanne Cranz-Mileva, Eve Reilly, Noor Chalhoub…·Mikel Zaratiegui

The paper shows that Tf2 retrotransposons in fission yeast provide a fitness benefit by modulating the host's transcriptional response to metabolic stress.

1 citation

yeastDNA methylation

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