Cell BiologyBlood AdvancesPeer-reviewed
Maintenance of haematopoietic stem cells by JAK inhibition and increased tyrosine-unphosphorylated STAT5
Matthew Williams, Xiaonan Wang, Hugo P. Bastos…·Anthony Richard Green
This study shows that JAK inhibition increases uSTAT5 levels, which promotes HSC maintenance and stemness, and reveals a new role for uSTAT5 in controlling HSC function.