Haixiao Chen

This study evaluates how blood storage conditions affect plasma cell-free RNA transcript profiles, finding that mRNA and lncRNA stability is highest at 4°C for 6 hours or RT for 2 hours.

This study assesses how temporary storage conditions affect the transcriptome of peripheral blood leukocytes, identifying gene expression changes and stable reference genes.

The paper evaluates five cfDNA isolation kits for plasma, finding that all can isolate cfDNA with varying efficiency, with VZ kit achieving 90% efficiency comparable to QC.

PALM-Seq simultaneously sequences cell-free long and small RNA, identifying pregnancy-related RNAs and sample-specific signatures in plasma, amniotic fluid, leukocytes, and placentas.

This study compares gene expression profiles of leukocytes from different isolation methods, finding that RBC lysis reduces globin mRNA and improves transcriptome quality.