Author

Zhongzhen Liu

BGI Group (China)ORCID 0000-0002-6435-345XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:deconvolution· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Wenjing WangiD· 3 shared Haixiao CheniD· 2 shared Jinghua SuniD· 2 shared Juan ZengiD· 2 shared Qing ZhouiD· 2 shared Sujun ZhuiD· 2 shared Chengbin Hu· 1 shared Chunyu GengiD· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersMolecular Biology

Wenjing WangORCID

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3 papers

Recent·Most cited

Pathway-enhanced Transformer-based robust model for quantifying cell types of origin of cell-free transcriptome

Shuo Yan, Xuetao Tian, Yulong Qin, Jiayi Li, Tingyu Yang, Dongyue Yu, Wentao Liu, Jinghua Sun, Chengbin Hu, Qing Zhou, Zhongzhen Liu, Wenjing Wang

Deconformer improves cell type deconvolution of cell-free RNA by integrating biological pathways, showing better performance and interpretability across multiple datasets.

bioRxiv · Feb 28, 2024 · PreprintBioinformatics

Evaluation of five cell-free DNA isolation kits for plasma

Zhongzhen Liu, Xi Yang, Haixiao Chen, Sujun Zhu, Juan Zeng, Fang Chen, Wenjing Wang

The paper evaluates five cfDNA isolation kits for plasma, finding that all can isolate cfDNA with varying efficiency, with VZ kit achieving 90% efficiency comparable to QC.

bioRxiv · Jul 26, 2019 · PreprintMolecular Biology

PALM-Seq: simultaneous sequencing of cell-free long RNA and small RNA

Xi Yang, Taifu Wang, Sujun Zhu, Juan Zeng, Yanru Xing, Qing Zhou, Zhongzhen Liu, Haixiao Chen, Jinghua Sun, Liqiang Li, Jinjin Xu, Chunyu Geng, Xun Xu, Jian Wang, Huanming Yang, , Wen-Jing Wang

PALM-Seq simultaneously sequences cell-free long and small RNA, identifying pregnancy-related RNAs and sample-specific signatures in plasma, amniotic fluid, leukocytes, and placentas.

bioRxiv · Jul 5, 2019 · PreprintMolecular Biology