Jun Zhao

This study shows that activating astrocytes in the visual cortex of rats triggers meningeal nociception and migraine-like behaviors by increasing nociceptor activity and pain sensitivity.

This study investigates how meningeal afferents respond to locomotion-related deformations in a migraine model, finding that CSD enhances sensitivity to these deformations.

This study shows that P2X7 and Pannexin 1 signaling in meninges mediates mechanical sensitization of afferents after CSD, contributing to migraine headache.

This study investigates the relationship between cortical spreading depression (CSD)-evoked metabolic changes and meningeal afferent activation in migraine, finding that metabolic perturbations are dissociated from afferent activation and sensitization.

This study investigates whether CGRP receptor antagonism affects meningeal afferent activation from K+ stimulation or CSD, finding suppression of K+-induced activation but not CSD-induced sensitization.