Matthew W. Foster

The paper identifies CYP2B10 as the enzyme that activates BHT into a toxic quinone methide, leading to apoptosis and lung damage in mice.

The paper develops a streamlined workflow for proteomic analysis of proteins and PTMs from dried blood, demonstrating feasibility and best practices for MS-based quantification.

The paper quantifies proteins and post-translational modifications in dried blood from sepsis patients in Tanzania, revealing proteome signatures of inflammation and correlations with clinical markers.

The paper identifies unique proteomic changes in ATTR-CM hearts, showing upregulated endocytosis and downregulated sarcomere proteins compared to controls.

The paper shows that K63 ubiquitin chains accumulate in non-cytosolic compartments during oxidative stress and that VCP/p97 and NPLOC4 regulate their localization and removal.

The paper introduces Acyl-Trap, a modified suspension trap assay for detecting and quantifying S-acylated proteins with low input, and identifies new S-acylation sites in mouse brain.

This study quantifies site-specific ribosome ubiquitination under oxidative stress and identifies stress-specific ubiquitin modification patterns.