Author

Jie Shi

Peking UniversityORCID 0000-0001-6567-8160Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Baizhen Zhao· 1 shared Ding Zengbo· 1 shared Fan Wang· 1 shared Haoyu Li· 1 shared Hei‐Man ChowiD· 1 shared Hongqiang SuniD· 1 shared Jacquelyne Ka‐Li SuniD· 1 shared Jiali LiiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMolecular Biology

Baizhen Zhao

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 24, 2026

An accumbal cholinergic ISR-HCN2 axis sustains maladaptive cue motivation

Shihao Huang, Jingliang Zhang, Yue Li…·Yan-Xue Xue

The paper identifies an ISR-HCN2 cholinergic mechanism in nucleus accumbens interneurons that sustains maladaptive cue-driven motivation and shows HCN blockade reduces cue-seeking behavior.

DOI 10.64898/2026.09.18.752826

mouseexperimental assay

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Molecular BiologybioRxivPreprintOct 30, 2023

The mtDNA-derived lncMtDloop promotes mitochondrial homeostasis maintenance and implications in AD

Wandi Xiong, Kaiyu Xu, Jacquelyne Ka‐Li Sun…·Jiali Li

This study identifies lncMtDloop as a regulator of mitochondrial homeostasis, showing reduced expression in AD and improved pathology with its overexpression.

1 citation

humanmouse

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GenomicsMolecular PsychiatryPeer-reviewedAug 28, 2019

Identification of novel risk loci with shared effects on alcoholism, heroin and methamphetamine dependence

Yan Sun, Suhua Chang, Zhen Liu…·Jie Shi

This study identifies four genome-wide significant SNPs shared across alcoholism, heroin, and methamphetamine dependence and links them to gene expression and brain structure.

38 citations

humanGWAS summary statistics

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