Author

Zhen‐Zhong Xu

Second Affiliated Hospital of Zhejiang UniversityORCID 0000-0001-6578-211XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:electronic health records· 1

Frequent Co-Authors

Ange Dai· 1 shared Cuicui JiaoiD· 1 shared Fang Xu· 1 shared Fangfang Zhu· 1 shared Gang CheniD· 1 shared Hao LuoiD· 1 shared Honghai ZhangiD· 1 shared Hua LiiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperNeuroscience

Ange Dai

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceeLifePeer-reviewedDec 23, 2025

GPR30 in spinal cholecystokinin-positive neurons modulates neuropathic pain

Qing Chen, Hui Bing K. Wu, Shulan Xie…·Xinzhong Chen

This study identifies GPR30 in spinal CCK+ neurons and S1-SDH postsynaptic neurons as critical for neuropathic pain, suggesting it as a therapeutic target.

1 citation

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceJCI InsightPeer-reviewedOct 4, 2022

mTOR-neuropeptide Y signaling sensitizes nociceptors to drive neuropathic pain

Lunhao Chen, Yaling Hu, Siyuan Wang…·Zhihua Gao

This study identifies mTOR and NPY/Y2R signaling as key drivers of neuropathic pain by enhancing nociceptor excitability through transcriptional induction of NPY.

40 citationstop 3%

mouseexperimental assay

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NeuroscienceCell ReportsPeer-reviewedNov 1, 2019

Interleukin-17 regulates neuron-glial communications, inhibitory synaptic transmission and neuropathic pain after chemotherapy

Hao Luo, Hui-Zhu Liu, Wenwen Zhang…·Yu‐Qiu Zhang

This study shows IL-17 from glia suppresses inhibitory synaptic transmission and drives neuropathic pain after chemotherapy.

162 citationstop 1%

mouseelectronic health records

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