NeurosciencebioRxivPreprint
Sparcl1/Hevin drives inflammatory and neuropathic pain through astrocyte and NMDA receptor signaling
Gang Chen, Hao Luo, Xin Luo…·Ru‐Rong Ji
This study shows hevin, an astrocyte-secreted protein, maintains chronic pain through NMDA receptor signaling, and neutralizing hevin may offer new therapeutic strategies for pain and neurodegeneration.