Marcello DiStasio

The paper uses computer models to predict differential dendritic vulnerability to ischemia and spreading depression, finding greater calcium accumulation in basilar dendrites and higher intracellular chloride in distal apical dendrites during ischemia.

This paper uses surprisal information-theoretic analysis on spatial transcriptomic data from human glioblastoma to uncover hidden spatial programs and interactions not detected by standard methods.

The paper identifies a novel population of titin-expressing macrophages in the choroid plexus and shows their altered function in Alzheimer's disease.

Spatial-CITE-seq profiles proteins and transcriptomes in tissues, revealing spatially distinct immune responses in mouse and human tissues.

A topological machine learning approach applied to single-nucleus RNA sequencing identifies shared glial activation states in AMD, AD, and MS.