Author

Hayley M. Pearson

University of LeedsORCID 0000-0001-6591-9884Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

John N. BarriD· 3 shared Amelia B. ShawiD· 1 shared Ana Carolina Gomes JardimiD· 1 shared Eleanor J. A. A. ToddiD· 1 shared Eric W. HewittiD· 1 shared Hiu Nam TseiD· 1 shared Jamel MankouriiD· 1 shared Jonathan D. LippiatiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

John N. BarrORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 14, 2026

Screening of MMV open-source libraries using Bunyamwera virus as a model reveals inhibitors of Oropouche virus infection

Natasha Marques Cassani, Hayley M. Pearson, John N. Barr…·Ana Carolina Gomes Jardim

The paper screens MMV libraries against Oropouche virus using Bunyamwera virus as a model, identifying GSK-983 as a promising inhibitor with low EC50 and high selectivity.

DOI 10.64898/2026.01.14.699453

proteomicsexperimental assay

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Cell BiologybioRxivPreprintJan 12, 2026

Host cell potassium ion channels KCNJ2 (KIR2.1), KCNJ13 (KIR7.1) and KCNMA1 (BKCa) mediate escape of Bunyamwera virus from late endosomal compartments

Hayley M. Pearson, Samantha E. Hover, Eleanor J. A. A. Todd…·John N. Barr

This study identifies KCNJ2, KCNJ13, and KCNMA1 as potassium channels facilitating Bunyamwera virus escape from late endosomes.

DOI 10.64898/2026.01.12.698685

humanexperimental assay

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MicrobiologybioRxivPreprintNov 18, 2025

The orthobunyavirus Gc glycoprotein head and stalk drives an infectious virion assembly pathway that is specific for the insect host

Amelia B. Shaw, Hiu Nam Tse, Molly V. Durawa…·John N. Barr

This study shows that the Gc glycoprotein head and stalk domains are essential for virion assembly in insect hosts but not in mammalian cells, explaining their conservation in nature.

DOI 10.1101/2025.11.18.689178

mousehuman

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